Blasticidin S hydrochloride (Synonyms: 殺稻瘟菌素鹽酸鹽;殺稻瘟菌素S鹽酸鹽;滅瘟素S鹽酸鹽)
Blasticidin S hydrochloride 是從 Streptomyces griseochromogenes 中分離的核苷抗生su (antibiotic)。Blasticidin S hydrochloride 抑制原核細(xì)胞和真核細(xì)胞中蛋白質(zhì)合成 (protein synthesis)。
生物活性:Blasticidin S hydrochloride is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. Blasticidin S hydrochloride is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells
IC50 & Target:Antibiotic
體外研究(In Vitro)
Blasticidin S (BlaS) is a broad spectrum antibiotic and inhibits cell growth in prokaryotes, fungi, plants, and mammalian cells
分子量:458.90
Formula:C17H27ClN8O5
CAS 號(hào):3513-03-9
中文名稱(chēng):殺稻瘟菌素鹽酸鹽;殺稻瘟菌素S鹽酸鹽;滅瘟素S鹽酸鹽
來(lái)源:Streptomyces griseochromogenes
運(yùn)輸條件:Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式:
-20°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性數(shù)據(jù)
H2O : 20 mg/mL (43.58 mM; Need ultrasonic)
濃度溶劑體積質(zhì)量 | 1 mg | 5 mg | 10 mg |
---|
1 mM | 2.1791 mL | 10.8956 mL | 21.7912 mL |
5 mM | 0.4358 mL | 2.1791 mL | 4.3582 mL |
10 mM | 0.2179 mL | 1.0896 mL | 2.1791 mL |
請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請(qǐng)分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 儲(chǔ)存時(shí),請(qǐng)?jiān)?6 個(gè)月內(nèi)使用,-20°C 儲(chǔ)存時(shí),請(qǐng)?jiān)?1 個(gè)月內(nèi)使用。
參考文獻(xiàn)
[1]. Kitamura K, et al. Critical role of the proton-dependent oligopeptide transporter (POT) in the cellular uptake of the peptidyl nucleoside antibiotic, blasticidin S. Biochim Biophys Acta Mol Cell Res. 2017 Feb;1864(2):393-398.
注:產(chǎn)品僅用于科研